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Sep 26, 2024

Can NAD+ reverse aging?

The American "Times" interviewed Greg, a biotechnologist and founder of SRW Labs, regarding the major scientific and technological achievements of anti-aging in human cells. Some of his views are worth pondering: "In the past ten years of research, scientists have There is consensus on nine key areas that function less as we age, and if cellular function deteriorates more, we age faster. " The World Health Organization's new definition of disease recovery, anti-aging: "Cure." The most fundamental way to fight disease and anti-aging is to repair cells, improve cell metabolism, and activate the functions of aging cells." Therefore, only when our cells are healthy can we maintain a healthy body at all times! In 2023, "Cell" published a blockbuster paper describing the twelve major signs of aging, revealing that the essence of human aging is cellular aging.

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Cells are the most basic structural and functional units of the human body. All life activities of the human body are inseparable from the support of cells. Cell health contributes to human health. If a person is sick, that is, the cells are damaged, poisoned or neglected, coupled with the attack of bacteria or viruses, weakening the functions of the cells, thus triggering the occurrence of various chronic diseases. The American medical website Medicine Net announced: After the age of 20, the body begins to gradually develop towards aging. At the same time, various diseases will follow one after another. This is ultimately caused by problems with the cells. The aging of the human body is a gradual process that begins at the age of 20, and the aging processes of different organs and tissues are not synchronized.

In the medical field, there are currently a large number of studies showing that the anti-aging factor NAD+ is involved in the metabolism of important substances such as sugar, fat, and protein in the human body, and plays a key role in regulating the body's material and energy metabolism and maintaining normal physiological functions. NAD is the most important coenzyme in the human body, also called coenzyme I. It participates in thousands of redox enzymatic reactions in the human body. It is an indispensable substance for the metabolism of every cell. Since NAD+ in the human body will continue to decrease with age, how to replenish a sufficient amount of NAD+ for our body is an important research idea in the field of anti-aging.

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Research has found that as long as NAD+ precursors are properly supplemented, it can help the body synthesize the required NAD+.

At the beginning of this century, American scientist Professor Charles Brenner subsequently discovered a precursor of NAD+, nicotinamide ribose (NR). NR-nicotinamide ribose is the earliest NAD+ precursor substance discovered. After NR enters the human body, it needs to be phosphorylated by NPK1-2 and converted into NMN, and then NMN is converted into NAD+. Related NAD+ precursor research is also "exploding" among the rich. Li Ka-shing once invested 200 million yuan in NAD+ precursor material projects, and Buffett also bet on the NAD+ precursor field.

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